David N Brindley Selected Research

Papillary Thyroid Cancer

12/2016	Platelet derived growth factor receptor alpha mediates nodal metastases in papillary thyroid cancer by driving the epithelial-mesenchymal transition.
10/2016	PDGFRα Regulates Follicular Cell Differentiation Driving Treatment Resistance and Disease Recurrence in Papillary Thyroid Cancer.
8/2015	Autotaxin is an inflammatory mediator and therapeutic target in thyroid cancer.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

David N Brindley Research Topics

Disease

46	Neoplasms (Cancer) 02/2024 - 08/2004
30	Breast Neoplasms (Breast Cancer) 02/2024 - 03/2007
26	Neoplasm Metastasis (Metastasis) 02/2024 - 08/2004
7	Inflammation (Inflammations) 12/2023 - 08/2004
5	Insulin Resistance 02/2015 - 06/2008
4	Infections 09/2021 - 10/2003
4	Obesity 04/2015 - 07/2008
3	Melanoma (Melanoma, Malignant) 02/2024 - 09/2009
3	Radiation Fibrosis Syndrome (Radiation Fibrosis) 08/2020 - 01/2020
3	Lipodystrophy 12/2017 - 02/2007
3	Papillary Thyroid Cancer 12/2016 - 08/2015
3	Pathologic Processes 11/2015 - 05/2009
2	Fibrosis (Cirrhosis) 04/2020 - 03/2018
2	Idiopathic Pulmonary Fibrosis 02/2020 - 01/2020
2	Thyroid Neoplasms (Thyroid Cancer) 08/2015 - 11/2014
2	Atherosclerosis 04/2015 - 06/2008
2	Wounds and Injuries (Trauma) 04/2006 - 08/2004
1	Carcinogenesis 06/2023
1	Lung Diseases (Lung Disease) 09/2021
1	Fetal Growth Retardation (Intrauterine Growth Retardation) 01/2021
1	Rhabdomyolysis 01/2021
1	Gestational Diabetes (Gestational Diabetes Mellitus) 01/2021
1	Pregnancy Complications 01/2021
1	Pre-Eclampsia (Preeclampsia) 01/2021
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2019
1	Ovarian Neoplasms (Ovarian Cancer) 01/2019
1	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2017
1	Lymphatic Metastasis 12/2016

Drug/Important Bio-Agent (IBA)

16	LipidsIBA 01/2022 - 08/2004
10	Proteins (Proteins, Gene)FDA Link 02/2022 - 08/2004
8	CytokinesIBA 12/2023 - 08/2015
7	Phosphates (Orthophosphate)IBA 01/2022 - 08/2004
6	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 06/2023 - 11/2007
5	ChemokinesIBA 12/2023 - 08/2015
5	Messenger RNA (mRNA)IBA 02/2022 - 07/2008
5	lysophosphatidic acidIBA 12/2020 - 11/2007
4	Lysophosphatidic Acid ReceptorsIBA 02/2024 - 11/2007
4	Lysophosphatidylcholines (Lysophosphatidylcholine)IBA 02/2024 - 08/2004
4	lipid phosphate phosphataseIBA 04/2023 - 03/2018
4	Doxorubicin (Adriamycin)FDA LinkGeneric 09/2021 - 01/2014
4	EnzymesIBA 01/2021 - 02/2007
4	ONO-8430506IBA 09/2015 - 06/2014
4	Fatty Acids (Saturated Fatty Acids)IBA 02/2015 - 03/2007
3	Dexamethasone (Maxidex)FDA LinkGeneric 04/2020 - 01/2019
3	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2020 - 08/2004
3	AntioxidantsIBA 02/2016 - 07/2014
3	Insulin (Novolin)FDA Link 02/2015 - 06/2008
3	lipineIBA 09/2012 - 02/2007
2	Monoclonal AntibodiesIBA 12/2023 - 12/2023
2	Infliximab (Remicade)FDA Link 12/2023 - 12/2023
2	Transcription Factors (Transcription Factor)IBA 12/2023 - 12/2008
2	RNA (Ribonucleic Acid)IBA 06/2023 - 04/2023
2	Viral DNAIBA 02/2022 - 03/2019
2	DNA (Deoxyribonucleic Acid)IBA 02/2022 - 09/2021
2	matrigelIBA 01/2022 - 01/2019
2	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 09/2021 - 12/2016
2	GLPG1690IBA 02/2020 - 01/2020
2	CollagenIBA 03/2019 - 01/2019
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2017 - 08/2015
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2017 - 09/2015
2	Docetaxel (Taxotere)FDA Link 01/2017 - 01/2014
2	Glucose (Dextrose)FDA LinkGeneric 02/2015 - 06/2008
2	Nonesterified Fatty Acids (NEFA)IBA 02/2015 - 06/2008
2	Triglycerides (Triacylglycerol)IBA 05/2010 - 12/2008
2	Eicosapentaenoic AcidIBA 12/2008 - 03/2007
2	Docosahexaenoic AcidsIBA 12/2008 - 03/2007
2	NF-kappa B (NF-kB)IBA 12/2008 - 01/2005
1	GTP-Binding Proteins (G-Protein)IBA 02/2024
1	AlbuminsIBA 02/2024
1	VimentinIBA 12/2023
1	ProlactinIBA 05/2023
1	Glycoproteins (Glycoprotein)IBA 02/2022
1	HydrogelsIBA 01/2022
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 09/2021
1	CeramidesIBA 01/2021
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/2021
1	Mitochondrial DNA (mtDNA)IBA 01/2021
1	Macrophage Colony-Stimulating FactorIBA 01/2020
1	Interleukin-9 (Interleukin 9)IBA 01/2020
1	Caspase 3 (Caspase-3)IBA 01/2020
1	AdiponectinIBA 11/2019
1	SphingolipidsIBA 01/2019
1	Cyclin D1IBA 01/2019
1	Matrix Metalloproteinases (MMPs)IBA 01/2019
1	Cyclin D3IBA 01/2019
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 01/2019
1	taxaneIBA 01/2017
1	Poly (ADP-Ribose) Polymerase-1IBA 01/2017
1	TetracyclinesIBA 01/2017
1	Doxycycline (Periostat)FDA LinkGeneric 01/2017
1	Vinca AlkaloidsIBA 01/2017
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2017
1	Interleukin-6 (Interleukin 6)IBA 01/2017
1	Colchicine FDA LinkGeneric 01/2017

Therapy/Procedure

16	Radiotherapy 05/2023 - 01/2013
15	Drug Therapy (Chemotherapy) 05/2023 - 09/2009
12	Therapeutics 02/2024 - 04/2007
2	Immunotherapy 02/2024 - 12/2020
1	Segmental Mastectomy (Lumpectomy) 11/2019
1	Lasers (Laser) 01/2017